Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 5/20 | 0.33 |
| ▸ | BACE1 | P56817 | 5/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558692 | 0.84 | TRPV1 (0.40) | TRPV1AKR1B1CFTR | |
| Hydrochloric Acid SCHEMBL7830696 | 0.83 | TRPV1 (0.40) | TRPV1AKR1B1CFTR | |
| SCHEMBL6558771 | 0.74 | KCNE1 (0.40) | TRPV1AKR1B1 | |
| SCHEMBL6558621 | 0.73 | TRPV1 (0.37) | TRPV1AKR1B1 | |
| SCHEMBL8069942 | 0.71 | TLR3 (0.41) | TRPV1AKR1B1 | |
| Hydrochloric Acid SCHEMBL6558725 | 0.70 | KDM1A (0.41) | TRPV1AKR1B1 | |
| SCHEMBL6558672 | 0.69 | TRPV1 (0.49) | TRPV1CTSDBACE1 | |
| SCHEMBL6558627 | 0.68 | TRPV1 (0.33) | TRPV1CTSDBACE1 | |
| SCHEMBL6560804 | 0.68 | TRPV1 (0.48) | TRPV1CTSDBACE1 | |
| SCHEMBL6558741 | 0.67 | TRPV1 (0.33) | TRPV1CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |