Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558692 | 0.81 | TRPV1 (0.40) | TRPV1KCNA5 | |
| Hydrochloric Acid SCHEMBL7830696 | 0.80 | TRPV1 (0.40) | TRPV1KCNA5 | |
| SCHEMBL6561008 | 0.78 | KCNE1 (0.37) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL6560820 | 0.77 | KCNA5 (0.36) | TRPV1KCNA5PKM | |
| SCHEMBL27520746 | 0.76 | TRPV1 (0.34) | TRPV1KCNA5CYP11B1CYP11B2 | |
| SCHEMBL6559589 | 0.76 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL6558621 | 0.76 | TRPV1 (0.37) | TRPV1KCNA5CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL6559571 | 0.75 | TSHR (0.35) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL6558599 | 0.74 | KDM4E (0.38) | TRPV1HPGDLMNA | |
| SCHEMBL6558641 | 0.72 | TRPV1 (0.39) | TRPV1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |