Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560018 | 0.95 | SMN1; SMN2 (0.35) | SMN1; SMN2LMNA | |
| SCHEMBL30009641 | 0.80 | AKR1C3 (0.36) | SMN1; SMN2LMNAFKBP1AALDH1A1L3MBTL1 | |
| SCHEMBL24453925 | 0.75 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6559583 | 0.70 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6559617 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6560000 | 0.67 | PRMT5 (0.40) | LMNAALDH1A1 | |
| SCHEMBL7812041 | 0.63 | EPHX1 (0.53) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28650978 | 0.62 | DPP4 (0.37) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28655579 | 0.62 | DPP4 (0.37) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8495444 | 0.62 | EPHX1 (0.56) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926164-B1 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | BASELL NORTH AMERICA INC (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6130180-A | Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds | MONTELL NORTH AMERICA INC. (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0926164-A2 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | MONTELL NORTH AMERICA INC. (US) | 1999-06-30 | — | — | EP | disclosed |