Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558731 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNAFKBP1AALDH1A1L3MBTL1 | |
| SCHEMBL28849318 | 0.80 | HPGD (0.37) | GAAHPGDALDH1A1EPHX2MEN1 | |
| SCHEMBL24453925 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAALDH1A1DPP4MEN1 | |
| SCHEMBL489632 | 0.76 | GAA (0.39) | SMN1; SMN2LMNAGAAHPGDALDH1A1 | |
| SCHEMBL6560018 | 0.75 | SMN1; SMN2 (0.35) | SMN1; SMN2LMNADPP4MEN1KMT2A | |
| SCHEMBL28780419 | 0.75 | POLB (0.33) | GAAHPGDRECQL | |
| SCHEMBL6559583 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAGAAALDH1A1MEN1 | |
| SCHEMBL6559617 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL13873135 | 0.71 | ALDH1A1 (0.53) | AKR1C3SMN1; SMN2LMNAGAAHPGD | |
| SCHEMBL4630563 | 0.71 | HPGD (0.38) | SMN1; SMN2LMNAGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |