Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558731 | 0.95 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNA | |
| SCHEMBL24453925 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNADPP4MEN1KMT2A | |
| SCHEMBL30009641 | 0.75 | AKR1C3 (0.36) | SMN1; SMN2LMNADPP4MEN1KMT2A | |
| SCHEMBL6559583 | 0.68 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6560857 | 0.66 | RIPK1 (0.42) | LMNA | |
| SCHEMBL6559617 | 0.66 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL12441738 | 0.64 | TSHR (0.42) | SMN1; SMN2LMNADPP4 | |
| SCHEMBL3243697 | 0.61 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3247378 | 0.61 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20997022 | 0.61 | KDM4E (0.36) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926164-B1 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | BASELL NORTH AMERICA INC (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6130180-A | Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds | MONTELL NORTH AMERICA INC. (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0926164-A2 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | MONTELL NORTH AMERICA INC. (US) | 1999-06-30 | — | — | EP | disclosed |