Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169257 | 0.95 | HTR2C (0.46) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL3159426 | 0.79 | TAAR1 (0.46) | HTR2CCHRNB4CHRNA3HTR2AHTR2B | |
| SCHEMBL3035320 | 0.79 | HTR2C (0.49) | HTR2CDRD2HTR2AHTR2BMEN1 | |
| SCHEMBL3153900 | 0.78 | ALDH1A1 (0.37) | SMN1; SMN2LMNAMAPTACHENPC1 | |
| SCHEMBL186274 | 0.77 | NOS1 (0.52) | HTR2CDRD3SLC6A3LMNAMAOB | |
| SCHEMBL7794528 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2LMNAMAPTKMT2ANPC1 | |
| SCHEMBL3173918 | 0.76 | NOS1 (0.50) | HTR2CDRD3SLC6A3LMNAMAOB | |
| SCHEMBL8542775 | 0.76 | NOS1 (0.50) | HTR2CDRD3SLC6A3LMNAMAOB | |
| SCHEMBL11313922 | 0.76 | HTR2C (0.41) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL7354887 | 0.74 | KDM1A (0.49) | HTR2CDRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926164-B1 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | BASELL NORTH AMERICA INC (US) | 2004-02-25 | — | — | EP | claimed |
| US-6130180-A | Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds | MONTELL NORTH AMERICA INC. (US) | 2000-10-10 | — | — | US | claimed |
| EP-0926164-A2 | Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them | MONTELL NORTH AMERICA INC. (US) | 1999-06-30 | — | — | EP | claimed |