Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 14/20 | 0.48 |
| ▸ | DRD2 | P14416 | 12/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145781 | 0.80 | DRD3 (0.41) | HTR1ADRD3DRD2GRIN2B | |
| SCHEMBL8145785 | 0.80 | DRD3 (0.41) | HTR1ADRD3DRD2GRIN2B | |
| SCHEMBL6561256 | 0.78 | DRD2 (0.67) | HTR1ADRD3DRD2DRD4 | |
| SCHEMBL30612408 | 0.78 | DRD2 (0.67) | HTR1ADRD3DRD2DRD4 | |
| SCHEMBL28997283 | 0.76 | DRD2 (0.67) | HTR1ADRD3DRD2DRD4 | |
| SCHEMBL30335277 | 0.76 | DRD2 (0.67) | HTR1ADRD3DRD2DRD4 | |
| SCHEMBL28997280 | 0.76 | DRD2 (0.67) | HTR1ADRD3DRD2DRD4 | |
| SCHEMBL28997284 | 0.76 | DRD2 (0.67) | HTR1ADRD3DRD2DRD4 | |
| SCHEMBL8886530 | 0.76 | DRD2 (0.49) | HTR1ADRD3DRD2 | |
| SCHEMBL7436227 | 0.74 | HTR1D (0.56) | HTR1ADRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091946-B1 | NEW 2-AMINOTHIAZOL-FUSED 2-AMINOINDANS AND 2-AMINOTETRALINS AND THEIR USE | WIKSTROEM HAKAN VILHELM (NL) | 2004-03-17 | — | — | EP | disclosed |
| US-6291494-B1 | 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins and their use | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | disclosed |
| EP-1091946-A1 | NEW 2-AMINOTHIAZOL-FUSED 2-AMINOINDANS AND 2-AMINOTETRALINS AND THEIR USE | WIKSTRÖM, Hakan Vilhelm (NL) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001680-A1 | NEW 2-AMINOTHIAZOL-FUSED 2-AMINOINDANS AND 2-AMINOTETRALINS AND THEIR USE | WIKSTROEM HAKAN VILHELM (NL) | 2000-01-13 | — | — | WO | disclosed |