Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19312229 | 0.86 | LMNA (0.48) | LMNAPOLBKDM4EADRA2CADRA2A | |
| SCHEMBL6560720 | 0.85 | LMNA (0.44) | LMNAPOLBKDM4EADRA2CADRA2A | |
| SCHEMBL14578020 | 0.84 | LMNA (0.47) | LMNAPOLBKDM4EADRA2CADRA2A | |
| SCHEMBL14578026 | 0.84 | LMNA (0.47) | LMNAPOLBKDM4EADRA2CADRA2A | |
| SCHEMBL9750485 | 0.83 | TAAR1 (0.42) | LMNAPOLBKDM4EADRA2AL3MBTL1 | |
| SCHEMBL6558978 | 0.82 | LMNA (0.41) | LMNAKDM4EADRA2CADRA2AHIF1A | |
| SCHEMBL17395998 | 0.82 | LMNA (0.50) | LMNAPOLBPPARGPPARAALDH1A1 | |
| SCHEMBL6558867 | 0.82 | ALDH1A1 (0.44) | LMNAPOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL12929842 | 0.81 | LMNA (0.44) | LMNAPOLBKDM4EPPARGPPARA | |
| SCHEMBL29097237 | 0.81 | PPARG (0.48) | LMNAPOLBKDM4EPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735403-B1 | Liquid crystal orienting agent | JSR CORP (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-5700860-A | Liquid crystal orienting agent | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0735403-A1 | Liquid crystal orienting agent | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |