Ethylene Glycol

Ethylene Glycol

SCHEMBL6558975

C=CC.C=CC.CCCCOc1ccccc1.OCCO

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.62
ALDH1A1 P00352 2/20 0.55
RECQL P46063 1/20 0.55
KCNA3 P22001 1/20 0.50
MLNR O43193 1/20 0.47
NR1I2 O75469 1/20 0.47
ESR1 P03372 1/20 0.47
NR3C1 P04150 1/20 0.47
PGR P06401 1/20 0.47
ADRB2 P07550 1/20 0.47
CHRM2 P08172 1/20 0.47
ADRB1 P08588 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CHRM1 P11229 1/20 0.47
DRD2 P14416 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
CHRM3 P20309 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL6558862 1.00 LTA4H (0.62) LTA4HALDH1A1RECQLKCNA3MLNR
Phenoxyethanol SCHEMBL17352446 0.92 ALDH1A1 (0.56) LTA4HALDH1A1RECQLKCNA3MLNR
Ethylene Glycol SCHEMBL6559796 0.91 RECQL (0.57) LTA4HALDH1A1RECQLKCNA3LMNA
Ethylene Glycol SCHEMBL6560717 0.91 RECQL (0.57) LTA4HALDH1A1RECQLKCNA3LMNA
Ethylene Glycol SCHEMBL6558275 0.91 LTA4H (0.69) LTA4HALDH1A1RECQLKCNA3MLNR
Ethylene Glycol SCHEMBL6558283 0.91 LTA4H (0.74) LTA4HALDH1A1RECQLKCNA3MLNR
Propene SCHEMBL27373052 0.87 LTA4H (0.70) LTA4HALDH1A1KCNA3MLNRNR1I2
Propene SCHEMBL27561096 0.86 LTA4H (0.68) LTA4HALDH1A1KCNA3MLNRNR1I2
Phenoxyethanol SCHEMBL5275965 0.85 ALDH1A1 (0.76) LTA4HALDH1A1RECQLKCNA3NR1I2
Ethylene Glycol SCHEMBL11084812 0.84 LTA4H (0.66) LTA4HALDH1A1RECQLKCNA3MLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1782877-A Anti-corrosion agent composition DAICEL CHEM (JP) 2006-06-07 CN disclosed
EP-0735403-B1 Liquid crystal orienting agent JSR CORP (JP) 2004-03-17 EP disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed
EP-0735403-A1 Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed