Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7744307 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Hydrogen Sulfide SCHEMBL15299830 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Bromide SCHEMBL239583 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Hydrochloric Acid SCHEMBL20731 | 0.97 | BBOX1 (0.43) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Charcoal, Activated SCHEMBL31185790 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Hydrochloric Acid SCHEMBL29448229 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Hydrochloric Acid SCHEMBL7744310 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Hydrochloric Acid SCHEMBL1579563 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Phosphine SCHEMBL29289427 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1BLMACHECHRM2 | |
| Hydrochloric Acid SCHEMBL28636641 | 0.93 | BBOX1 (0.41) | BBOX1ALDH1A1BLMACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919578-B1 | Polymers suitable for paper making additives and process of manufacturing them | MITSUI CHEMICALS INC (JP) | 2004-02-11 | — | — | EP | disclosed |
| US-6255400-B1 | HIGH MOLECULAR WEIGHT, LOW VISCOSITY NONCROSSLINKED ADDITION COPOLYMER INCLUDING SULFONIC ACID UNITS, IONIC MONOMER UNITS AND (METH)ACRYLAMIDE UNITS; PAPER STRENGTHENING AGENT, DRAINAGE AID | MITSUI CHEMICALS, INC. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0919578-A1 | Polymers suitable for paper making additives and process of manufacturing them | Mitsui Chemicals, Inc. (JP) | 1999-06-02 | — | — | EP | disclosed |