Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20731 | 1.00 | BBOX1 (0.43) | BBOX1BLMALDH1A1TSHRACHE | |
| Hydrogen Sulfide SCHEMBL15299830 | 1.00 | BBOX1 (0.43) | BBOX1BLMALDH1A1TSHRACHE | |
| Charcoal, Activated SCHEMBL31185790 | 0.97 | BBOX1 (0.41) | BBOX1BLMALDH1A1TSHRACHE | |
| Phosphine SCHEMBL29289427 | 0.97 | BBOX1 (0.41) | BBOX1BLMALDH1A1TSHRACHE | |
| Hydrochloric Acid SCHEMBL29448229 | 0.97 | BBOX1 (0.41) | BBOX1BLMALDH1A1TSHRACHE | |
| Bromide SCHEMBL6559007 | 0.97 | BBOX1 (0.41) | BBOX1BLMALDH1A1TSHRACHE | |
| Hydrochloric Acid SCHEMBL7744310 | 0.97 | BBOX1 (0.41) | BBOX1BLMALDH1A1TSHRACHE | |
| Hydrochloric Acid SCHEMBL28636641 | 0.97 | BBOX1 (0.41) | BBOX1BLMALDH1A1TSHRACHE | |
| Hydrochloric Acid SCHEMBL1579563 | 0.97 | BBOX1 (0.41) | BBOX1BLMALDH1A1TSHRACHE | |
| Water SCHEMBL4391926 | 0.97 | BBOX1 (0.41) | BBOX1BLMALDH1A1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153978-A | Use the method for polydiene ammonium separation adeno-associated virus | 隆萨休斯敦股份有限公司 | 2019-01-04 | — | — | CN | disclosed |
| EP-3386288-A1 | SEED TREATMENT USING HYDROSWELLABLE POLYMER | S.P.C.M. SA (FR) | 2018-10-17 | — | — | EP | disclosed |
| CN-105984923-A | Leather sewage processing method | 王志龙 | 2016-10-05 | — | — | CN | disclosed |
| CN-104944543-A | Treatment method of leather sewage | LIU CONGTANG | 2015-09-30 | — | — | CN | disclosed |
| CN-104936988-A | Crosslinking of swellable polymers with PEI | CONOCOPHILLIPS CO | 2015-09-23 | — | — | CN | disclosed |
| CN-103964557-B | A kind of method utilizing paper mill sludge to prepare positively charged ion organic floculant | SHANDONG UNIVERSITY (CN) | 2015-08-19 | — | — | CN | disclosed |
| WO-2014144025-A1 | DEWATERING COMPOSITIONS AND METHODS | DOBER CHEMICAL CORP. (US) | 2014-09-18 | — | — | WO | disclosed |
| CN-103964557-A | Method for preparing cationic organic flocculant by using paper-making sludge | UNIV SHANDONG | 2014-08-06 | — | — | CN | disclosed |
| CN-102079563-B | Regenerative coagulant, and preparation method and using method thereof | UNIV DONGHUA | 2012-07-25 | — | — | CN | disclosed |
| CN-102079563-A | Regenerative coagulant, and preparation method and using method thereof | UNIV DONGHUA | 2011-06-01 | — | — | CN | disclosed |
| CN-101490229-A | Aqueous dispersion of hybrid coacervates imparting specific properties to solid surfaces and comprising particles of inorganic solid and copolymer | RHODIA (US) | 2009-07-22 | — | — | CN | disclosed |
| EP-1105572-A1 | A PROCESS TO IMPROVE THE DRAINAGE RATE AND RETENTION OF FINES DURING PAPERMAKING | BetzDearborn Inc (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6168686-B1 | ADDING CATIONIC OR AMPHOTERIC STARCH, AND A CATIONIC POLYELECTROLYTE FOLLOWED BY THE ADDITION OF A HIGH MOLECULAR WEIGHT ANIONIC POLYACRYLAMIDE COPOLYMER; IMPROVED RETENTION AND/OR DRAINAGE PROPERTIES OF MECHANICAL PULP-BASED FURNISH | BETZDEARBORN, INC. | 2001-01-02 | — | — | US | disclosed |
| WO-2000011267-A1 | A PROCESS TO IMPROVE THE DRAINAGE RATE AND RETENTION OF FINES DURING PAPERMAKING | BETZDEARBORN INC. (US) | 2000-03-02 | — | — | WO | disclosed |