Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | RHOC | P08134 | 1/20 | 0.56 |
| ▸ | RHOA | P61586 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127722 | 0.87 | PTGS1 (0.77) | PTGS1NPC1RAB9ALMNAMAPT | |
| SCHEMBL4463935 | 0.87 | PTGS1 (0.89) | PTGS1RAB9ALMNAMAPTKCNK3 | |
| SCHEMBL548237 | 0.86 | PTGS1 (0.77) | PTGS1NPC1RAB9ALMNAMAPT | |
| SCHEMBL11593046 | 0.86 | PTGS1 (0.75) | PTGS1NPC1RAB9ALMNAMAPT | |
| SCHEMBL3454009 | 0.85 | PTGS1 (1.00) | PTGS1NPC1RAB9ALMNAMAPT | |
| SCHEMBL17744815 | 0.84 | KMT2A (0.73) | PTGS1LMNAMAPTMEN1KMT2A | |
| SCHEMBL309467 | 0.84 | PTGS1 (0.72) | PTGS1LMNAMAPTMEN1KMT2A | |
| SCHEMBL31171945 | 0.84 | PTGS1 (0.72) | PTGS1LMNAMAPTMEN1KMT2A | |
| SCHEMBL2861430 | 0.84 | PTGS1 (1.00) | PTGS1RAB9ALMNAMAPTKCNK3 | |
| SCHEMBL21588759 | 0.84 | PTGS1 (0.72) | PTGS1NPC1RAB9AKCNK3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |
| EP-0735403-B1 | Liquid crystal orienting agent | JSR CORP (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-5700860-A | Liquid crystal orienting agent | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0735403-A1 | Liquid crystal orienting agent | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |