SCHEMBL548237

SCHEMBL548237

Nc1cc(N)cc(C(=O)Nc2ccc(C(F)(F)F)cc2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.77
NPC1 O15118 2/20 0.66
RAB9A P51151 2/20 0.66
TRPV1 Q8NER1 3/20 0.62
HDAC3 O15379 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
RORC P51449 1/20 0.60
P2RY14 Q15391 1/20 0.56
MEN1 O00255 2/20 0.56
LMNA P02545 2/20 0.56
KMT2A Q03164 2/20 0.56
POLB P06746 1/20 0.56
PKM P14618 1/20 0.56
APEX1 P27695 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
EPHX2 P34913 1/20 0.56
MAPT P10636 2/20 0.55
XBP1 P17861 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678654 0.87 PTGS1 (1.00) PTGS1NPC1RAB9ATRPV1HDAC3
SCHEMBL6559364 0.86 PTGS1 (1.00) PTGS1NPC1RAB9ATRPV1MEN1
SCHEMBL12540695 0.86 MEN1 (0.67) PTGS1NPC1RAB9AMEN1LMNA
SCHEMBL28329635 0.85 P2RX1 (0.64) PTGS1HDAC3HDAC8HDAC6MAPT
SCHEMBL7513604 0.84 TRPV1 (0.83) PTGS1NPC1RAB9ATRPV1HDAC3
SCHEMBL678064 0.84 PTGS1 (0.77) PTGS1NPC1RAB9ATRPV1HDAC3
SCHEMBL22387581 0.83 LMNA (0.67) PTGS1NPC1RAB9AHDAC3HDAC8
SCHEMBL549108 0.83 MAPT (0.73) PTGS1RAB9AMEN1LMNAKMT2A
SCHEMBL9318389 0.83 POLB (0.74) PTGS1NPC1RAB9AMEN1LMNA
SCHEMBL23060640 0.81 NPC1 (0.66) PTGS1NPC1RAB9ATRPV1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5756649-A HAVING THE ABILITY TO CHANGE THE PRETILT ANGLE WITH RADIATION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-26 US claimed
US-12386258-B2 Chain extenders and formulations thereof for improving elongation in photosensitive polyimide HUTCHINSON TECHNOLOGY INCORPORATED (US) 2025-08-12 US disclosed
US-12269948-B2 Polyimide precursor solution and method for producing porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2025-04-08 US disclosed
WO-2025070655-A1 MATERIAL FOR PRINTED WIRING BOARDS AND METHOD FOR MANUFACTURING PRINTED WIRING BOARD 東洋アルミニウム株式会社 2025-04-03 WO disclosed
WO-2025070654-A1 MATERIAL FOR PRINTED WIRING BOARDS AND METHOD FOR MANUFACTURING PRINTED WIRING BOARD 東洋アルミニウム株式会社 2025-04-03 WO disclosed
US-12259671-B2 Resin belt, fixing belt, fixing device, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2025-03-25 US disclosed
US-12253815-B2 Endless belt, fixing belt, fixing device, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2025-03-18 US disclosed
US-12247103-B2 Polyimide precursor solution, porous polyimide film, separator for secondary battery, and secondary battery FUJIFILM BUSINESS INNOVATION CORP. (JP) 2025-03-11 US disclosed
CN-113054322-B Porous polyimide film, separator for secondary battery, and secondary battery 富士胶片商业创新有限公司 2025-03-04 CN disclosed
US-12174571-B2 Fixing belt including layer of polyimide and specific filler, fixing device including the fixing belt, and image forming apparatus including the fixing device FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-12-24 US disclosed
US-20010056174-A1 Epoxy-modified polyimide, photosensitive composition, coverlay film, solder resist, and printed wiring board using the epoxy-modified polyimide KANEKA CORPORATION (JP) 2001-12-27 US disclosed
US-6307002-B1 POLYIMIDES FROM TETRAACIDS AND DIAMINES KANEKA CORPORATION (JP) 2001-10-23 US disclosed
US-6303742-B1 CHARACTERIZED BY A CINNAMOYL GROUP OR A DERIVED CINNAMOYL GROUP INCORPORATED THEREIN AND BY PHOTO-REACTIVITY AND HEAT-REACTIVITY WHICH ARE INHERENT IN THE CINNAMOYL GROUP. KANEKAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-10-16 US disclosed
US-5773559-A POLYAMIC ACID, POLYIMIDE BLOCK POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-30 US disclosed
US-5756649-A HAVING THE ABILITY TO CHANGE THE PRETILT ANGLE WITH RADIATION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-26 US disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed
US-5612450-A POLYAMIC ACID-POLYIMIDE COPOLYMER FILMS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0735403-A1 Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed
EP-0683418-A2 Liquid crystal aligning agent and liquid crystal display device JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-11-22 EP disclosed
EP-0675148-A1 Polymer film for liquid crystal display element TORAY INDUSTRIES, INC. (JP) 1995-10-04 EP disclosed