Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061522 | 0.88 | P2RX7 (0.52) | TSHRMAPTAKR1B1P2RX7 | |
| SCHEMBL1478685 | 0.87 | TSHR (0.46) | TSHRBRD4BRD2BRD3BRDT | |
| SCHEMBL30751420 | 0.85 | AAK1 (0.47) | GAASMN1; SMN2 | |
| SCHEMBL1476859 | 0.85 | AAK1 (0.47) | GAASMN1; SMN2 | |
| SCHEMBL1477663 | 0.84 | SETDB1 (0.56) | BRD4BRD2BRD3BRDTAKR1B1 | |
| SCHEMBL10202757 | 0.83 | HPGD (0.45) | TSHRMAPTSMN1; SMN2SETDB1P2RX7 | |
| SCHEMBL15657220 | 0.83 | SETDB1 (0.45) | TSHRALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL1759206 | 0.83 | TSHR (0.55) | TSHRALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL2749081 | 0.82 | ALDH1A1 (0.42) | TSHRBRD4BRD2BRD3BRDT | |
| SCHEMBL2526148 | 0.82 | SETDB1 (0.43) | BRD4BRD2BRD3BRDTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085010-B1 | PHENYLACETYLENE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-6313071-B1 | Phenylacetylene derivatives and agricultural/horticultural fungicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1085010-A1 | PHENYLACETYLENE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |