SCHEMBL65597

SCHEMBL65597

C=C(C)C(=O)OCC[SiH2]C(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136875 0.90 TSHR (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28866107 0.88 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16537856 0.88 TSHR (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL26918769 0.87 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL21066699 0.87 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL23923099 0.87 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1024055 0.87 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16537216 0.87 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL65281 0.84 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28228982 0.82 TSHR (0.46) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
CN-118459684-A Impact modifier, preparation method and modified resin 中化学科学技术研究有限公司 2024-08-09 CN disclosed
CN-118369388-A Water paint 株式会社钟化 2024-07-19 CN disclosed
US-12030973-B2 Thermoplastic resin composition and molded article of same TECHNO-UMG CO., LTD. (JP) 2024-07-09 US disclosed
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN disclosed
EP-4153682-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-06-05 EP disclosed
EP-4153681-B1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2024-05-29 EP disclosed
US-20240092961-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TECHNO-UMG CO., LTD. (JP) 2024-03-21 US disclosed
US-20240052165-A1 RESIN COMPOSITION AND MOLDED BODY MITSUBISHI CHEMICAL CORPORATION (JP) 2024-02-15 US disclosed
EP-4317229-A1 POLYORGANOSILOXANE-CONTAINING POLYMER, COMPOSITION, AND MOLDED ARTICLE Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
EP-0369376-A2 Flame retardant polyphenylene ether resin composition MITSUBISHI RAYON CO., LTD. (JP) 1990-05-23 EP disclosed
US-4918132-A Thermoplastic polyester resin composition MITSUBISHI RAYON COMPANY LIMITED (JP) 1990-04-17 US disclosed
US-4894415-A BLENDS, FRAFT COPOLYMERS, POLYALKYL (METH)ACRYLATE MITSUBISHI RAYON CO., LTD. (JP) 1990-01-16 US disclosed
US-4892900-A CONTAINING POLYSILOXANE GRAFT POLYMER, IMPROVED IMPACT STRENGTH MITSUBISHI RAYON CO., LTD. (JP) 1990-01-09 US disclosed
US-4888388-A BLENDS WITH POLYESTERS AND GRAFTED POLYSILOXANE-ACRYLIC POLYMERS MITSUBISHI RAYON COMPANY LIMITED (JP) 1989-12-19 US disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed
US-4775712-A BLENDS WITH POLYSILOXANES-IMPACT STRENGTH, HEAT AND COLD RESISTANT, WEATHERPROOFING-MOLDING MATERIALS MITSUBISHI RAYON CO., LTD. (JP) 1988-10-04 US disclosed
EP-0260552-A2 Graft copolymer rubber and polyphenylene ether resin composition comprising this rubber. MITSUBISHI RAYON CO., LTD. (JP) 1988-03-23 EP disclosed
US-4690986-A Impact-resistant thermoplastic polyorganosiloxane-based graft copolymer and process for producing same MITSUBISHI RAYON CO., LTD. (JP) 1987-09-01 US disclosed