SCHEMBL6559700

SCHEMBL6559700

C=CS(=O)(=O)c1cccc(C(=O)Nc2ccc(S(=O)(=O)O)c3cc(S(=O)(=O)O)cc(O)c23)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.59
TIMP3 P35625 5/20 0.59
RECQL P46063 5/20 0.59
HSD17B10 Q99714 5/20 0.59
TDP1 Q9NUW8 5/20 0.59
MEN1 O00255 4/20 0.59
ALDH1A1 P00352 4/20 0.59
USP2 O75604 2/20 0.59
HPSE Q9Y251 4/20 0.52
MAPT P10636 4/20 0.52
PKM P14618 4/20 0.52
P2RX1 P51575 4/20 0.52
P2RX3 P56373 4/20 0.52
SIRT2 Q8IXJ6 4/20 0.52
SIRT1 Q96EB6 4/20 0.52
P2RY11 Q96G91 3/20 0.52
BRCA1 P38398 2/20 0.52
ENPP3 O14638 1/20 0.52
ENTPD3 O75355 1/20 0.52
NR1I2 O75469 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11509490 0.85 TIMP3 (0.64) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL6562581 0.85 KMT2A (0.58) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL30818027 0.85 APEX1 (0.66) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL4649703 0.85 APEX1 (0.66) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL6560525 0.84 HSD17B10 (0.62) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL9319495 0.83 KMT2A (0.56) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL6562086 0.83 APEX1 (0.71) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL11511316 0.82 RECQL (0.71) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL10413406 0.81 MEN1 (0.58) KMT2ATIMP3RECQLHSD17B10TDP1
SCHEMBL6561268 0.80 APEX1 (0.43) KMT2ATIMP3RECQLHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055710-B1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-08-11 EP disclosed
US-6444794-B1 COMPLEXING WITH SUBSTRATE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-09-03 US disclosed
EP-1055710-A1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-29 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
EP-0629667-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1998-02-25 EP disclosed
EP-0548795-B1 Water-soluble reactive dyes, their manufacture and their use HOECHST AG (DE) 1997-07-09 EP disclosed
EP-0542214-A2 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
EP-0511246-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE. HOECHST AG (DE) 1992-11-04 EP disclosed
US-5138041-A Water-soluble fiber-reactive monoazo and disazo dyestuffs having a s-triazinylamino group and three fiber-reactive groups of the vinylsulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
EP-0471702-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE. HOECHST AG (DE) 1992-02-26 EP disclosed
WO-1991010709-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-25 WO disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed
EP-0388864-A2 Water-soluble, fibre-reactive dyes, method of their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-26 EP disclosed
EP-0385426-A1 Water soluble reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-05 EP disclosed
EP-0377166-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-11 EP disclosed