SCHEMBL6562086

SCHEMBL6562086

C=CS(=O)(=O)c1cccc(C(=O)Nc2cc(S(=O)(=O)O)cc3cc(S(=O)(=O)O)cc(O)c23)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 0.71
ENPP2 Q13822 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 2/20 0.41
USP2 O75604 1/20 0.41
TIMP3 P35625 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11694568 0.86 APEX1 (0.74) APEX1ENPP2MAOAMAOBMEN1
SCHEMBL11593854 0.86 APEX1 (0.81) APEX1ENPP2MAOAMAOBMEN1
SCHEMBL11595946 0.85 APEX1 (0.72) APEX1ENPP2MAOAMAOBMEN1
SCHEMBL10876642 0.84 APEX1 (0.77) APEX1ENPP2MEN1KMT2AALDH1A1
SCHEMBL6562298 0.83 APEX1 (0.54) APEX1MEN1KMT2AALDH1A1HSD17B10
SCHEMBL9411865 0.83 APEX1 (1.00) APEX1ENPP2MEN1KMT2AALDH1A1
SCHEMBL1413131 0.83 APEX1 (1.00) APEX1ENPP2MEN1KMT2AALDH1A1
SCHEMBL6559700 0.83 KMT2A (0.59) APEX1MEN1KMT2AALDH1A1HSD17B10
SCHEMBL5567709 0.83 APEX1 (0.76) APEX1ENPP2MAOAMAOBMEN1
SCHEMBL10944877 0.83 APEX1 (0.76) APEX1ENPP2MAOAMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055710-B1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-08-11 EP disclosed
US-6444794-B1 COMPLEXING WITH SUBSTRATE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-09-03 US disclosed
EP-1055710-A1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-29 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
EP-0629667-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1998-02-25 EP disclosed
EP-0548795-B1 Water-soluble reactive dyes, their manufacture and their use HOECHST AG (DE) 1997-07-09 EP disclosed
EP-0471713-A1 WATER-SOLUBLE AZO DYES, PROCESS FOR PRODUCING THEM AND THEIR USE. HOECHST AG (DE) 1992-02-26 EP disclosed
EP-0471702-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE. HOECHST AG (DE) 1992-02-26 EP disclosed
WO-1991010709-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-25 WO disclosed
US-5021558-A Color strength, fastness HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
WO-1990013603-A1 WATER-SOLUBLE AZO DYES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed
EP-0388864-A2 Water-soluble, fibre-reactive dyes, method of their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-26 EP disclosed
EP-0385426-A1 Water soluble reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-05 EP disclosed
EP-0377166-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-11 EP disclosed
EP-0374758-A1 Water soluble dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed