Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5949407 | 0.98 | MAOA (0.51) | MAOAMAOBNPC1RAB9APTPRA | |
| SCHEMBL9491676 | 0.82 | KDM4E (0.63) | MAOAMAOBPTPRAKDM4EGRIN2D | |
| SCHEMBL22728750 | 0.82 | KDM4E (0.63) | MAOAMAOBPTPRAKDM4EGRIN2D | |
| SCHEMBL27701885 | 0.81 | MAOA (0.49) | MAOAMAOBNPC1RAB9APTPRA | |
| SCHEMBL5949509 | 0.80 | IGF1R (0.50) | PTPRAKDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5949323 | 0.80 | IGF1R (0.50) | PTPRAKDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5948990 | 0.80 | IGF1R (0.50) | PTPRAKDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5949524 | 0.79 | PTPRA (0.46) | NPC1RAB9APTPRAKDM4EGRIN2D | |
| SCHEMBL11084913 | 0.79 | MEN1 (0.50) | NPC1RAB9APTPRAKDM4EGRIN2D | |
| SCHEMBL27701887 | 0.78 | MAOA (0.49) | MAOAMAOBNPC1RAB9APTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100371326-C | New substituted pyridine or pyridine compound, their producing process and pharmaceutical composition containing them | ADIR (FR) | 2008-02-27 | — | — | CN | claimed |
| EP-1050531-B1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | SERVIER LAB (FR) | 2004-11-17 | — | — | EP | claimed |
| EP-1050531-B1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | SERVIER LAB (FR) | 2004-11-17 | — | — | EP | disclosed |
| EP-1050531-A1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |