Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543486 | 0.81 | PTPRA (0.50) | PTPRAFDPSNPC1RAB9AKMT2A | |
| SCHEMBL6559702 | 0.81 | MAOA (0.52) | MAOAMAOBPTPRAGAAALDH1A1 | |
| Iodide SCHEMBL5949407 | 0.80 | MAOA (0.51) | MAOAMAOBPTPRAGAAALDH1A1 | |
| SCHEMBL27701887 | 0.78 | MAOA (0.49) | MAOAMAOBPTPRAGAAALDH1A1 | |
| SCHEMBL7829956 | 0.74 | PTPRA (0.65) | PTPRAALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL7829954 | 0.74 | PTPRA (0.65) | PTPRAALDH1A1FDPSNPC1RAB9A | |
| SCHEMBL5948753 | 0.72 | RAB9A (0.66) | MAOAMAOBALDH1A1NPC1RAB9A | |
| SCHEMBL5862097 | 0.72 | EPHX1 (0.60) | PTPRAALDH1A1FDPSGRIN2DGRIN3B | |
| SCHEMBL25214176 | 0.71 | PTPRA (0.53) | PTPRAFDPSNPC1RAB9AKMT2A | |
| SCHEMBL27628033 | 0.71 | PTPRA (0.55) | PTPRAALDH1A1L3MBTL1FDPSRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100371326-C | New substituted pyridine or pyridine compound, their producing process and pharmaceutical composition containing them | ADIR (FR) | 2008-02-27 | — | — | CN | disclosed |
| CN-1277192-A | New substituted pyridine or pyridine compound, their producing process and pharmaceutical composition containing them | ADIR (FR) | 2000-12-20 | — | — | CN | disclosed |