Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560544 | 0.79 | BRD4 (0.49) | ENPP1ENPP3 | |
| SCHEMBL5736045 | 0.79 | HTR7 (0.63) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL29904797 | 0.78 | HTR7 (1.00) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7807464 | 0.77 | ENPP1 (0.44) | HTR7ALDH1A1SMN1; SMN2ENPP1ENPP3 | |
| SCHEMBL6669102 | 0.77 | HTR7 (0.65) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| Irampanel SCHEMBL678128 | 0.76 | HTR7 (0.63) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6560831 | 0.76 | HTR7 (0.63) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6670234 | 0.75 | HTR7 (0.67) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7944194 | 0.75 | CXCR1 (0.64) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| Irampanel SCHEMBL6879876 | 0.75 | HTR7 (0.62) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |