Ethylene Glycol

Ethylene Glycol

SCHEMBL6559749

CC(C)(C)Oc1ccccc1.OCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
RECQL P46063 1/20 0.46
PPARA Q07869 5/20 0.42
PPARG P37231 6/20 0.40
LTA4H P09960 2/20 0.39
CA4 P22748 1/20 0.39
KIF11 P52732 1/20 0.38
LMNA P02545 1/20 0.38
RIPK1 Q13546 1/20 0.37
CYP2D6 P10635 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
PPARD Q03181 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL6560506 0.90 ALDH1A1 (0.39) ALDH1A1RECQLPPARAPPARGLTA4H
SCHEMBL93074 0.88 CA4 (0.48) ALDH1A1PPARAPPARGLTA4HCA4
SCHEMBL10405698 0.88 CA4 (0.48) ALDH1A1PPARAPPARGLTA4HCA4
Di(Hydroxyethyl)Ether SCHEMBL6559768 0.88 ALDH1A1 (0.50) ALDH1A1RECQLPPARAPPARGLTA4H
Phosphine SCHEMBL20897416 0.85 CA4 (0.46) ALDH1A1PPARAPPARGLTA4HCA4
Ammonia Solution, Strong SCHEMBL27478584 0.85 CA4 (0.46) ALDH1A1PPARAPPARGLTA4HCA4
Ethylene Glycol SCHEMBL10399388 0.84 ALDH1A1 (0.45) ALDH1A1RECQLPPARAPPARGLTA4H
Propylene Glycol SCHEMBL6558523 0.84 LMNA (0.50) ALDH1A1RECQLPPARAPPARGLMNA
Ethylene SCHEMBL27614909 0.83 CA4 (0.43) ALDH1A1PPARAPPARGLTA4HCA4
Methylamine SCHEMBL27799291 0.83 CA4 (0.43) ALDH1A1PPARGLTA4HCA4KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735403-B1 Liquid crystal orienting agent JSR CORP (JP) 2004-03-17 EP disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed
EP-0735403-A1 Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed