Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 4/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559311 | 0.91 | KCNE1 (0.52) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6560833 | 0.91 | KCNE1 (0.50) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6558723 | 0.89 | KCNE1 (0.63) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6558719 | 0.86 | KCNE1 (0.46) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6558706 | 0.84 | KCNE1 (0.66) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6559266 | 0.82 | KCNE1 (0.52) | KCNE1KCNQ1CYP3A4 | |
| SCHEMBL6559417 | 0.82 | KCNE1 (0.37) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6559947 | 0.81 | KCNE1 (0.51) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL7830283 | 0.81 | KCNE1 (0.36) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6559337 | 0.81 | KCNE1 (0.47) | KCNE1KCNQ1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |