Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557428 | 0.85 | POLB (0.56) | KMT2AMEN1RAB9AKDM4ENPC1 | |
| SCHEMBL1816768 | 0.85 | POLB (0.56) | KMT2AMEN1RAB9AKDM4ENPC1 | |
| SCHEMBL6841567 | 0.84 | KMT2A (0.57) | KMT2AMEN1RAB9AKDM4ENPC1 | |
| SCHEMBL9768242 | 0.83 | ALPG (0.50) | KMT2AMEN1KDM4ENPC1HPGD | |
| SCHEMBL8704295 | 0.81 | GAA (0.55) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL5123431 | 0.81 | GAA (0.55) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5774955 | 0.80 | GAA (0.53) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL3315763 | 0.79 | KMT2A (1.00) | KMT2AMEN1RAB9ANPC1HPGD | |
| SCHEMBL29287986 | 0.79 | SMN1; SMN2 (0.52) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5320792 | 0.78 | RAB9A (0.65) | KMT2AMEN1RAB9AAGTR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |
| EP-1071670-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054314-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |
| WO-1998045260-A1 | PROCESS FOR STEREOSELECTIVE PREPARATION OF AZETIDINONES | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1998-10-15 | — | — | WO | disclosed |