Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 10/20 | 0.73 |
| ▸ | HTR6 | P50406 | 6/20 | 0.73 |
| ▸ | HTR1A | P08908 | 6/20 | 0.73 |
| ▸ | HTR2A | P28223 | 2/20 | 0.73 |
| ▸ | HTR5A | P47898 | 2/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | HTR3A | P46098 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588593 | 0.86 | ADRB1 (0.58) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL3759275 | 0.84 | HTR7 (1.00) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL30022433 | 0.84 | HTR7 (1.00) | HTR7HTR6HTR1AHTR2AHTR5A | |
| Hydrochloric Acid SCHEMBL1673713 | 0.83 | HTR7 (0.96) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL4914927 | 0.81 | HTR7 (0.73) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL4915187 | 0.81 | HTR7 (0.73) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL7085636 | 0.81 | HTR7 (0.73) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL19640696 | 0.79 | MAPT (0.51) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL27706644 | 0.79 | HTR7 (0.56) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL19640677 | 0.78 | PDCD1 (0.49) | HTR7HTR6HTR1AHTR2AHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138678-B1 | Process for making N-((4-phenyl) methylphenyl) piperazines | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-1138678-A3 | Process for making N-((4-phenyl) methylphenyl) piperazines | SUNTORY LIMITED (JP) | 2001-10-17 | — | — | EP | disclosed |
| EP-1138678-A2 | Process for making N-((4-phenyl) methylphenyl) piperazines | SUNTORY LIMITED (JP) | 2001-10-04 | — | — | EP | disclosed |