Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PKLR | P30613 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078001 | 0.84 | IKBKB (0.57) | KMT2AMEN1 | |
| SCHEMBL9942091 | 0.83 | ATM (0.68) | KMT2AMEN1GAAATMPIK3CB | |
| SCHEMBL20021987 | 0.82 | PGR (0.77) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL28396503 | 0.82 | PGR (0.77) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL29549847 | 0.82 | PGR (0.77) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL1094118 | 0.81 | MEN1 (0.73) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL31661903 | 0.81 | MEN1 (0.73) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL6979083 | 0.77 | SMN1; SMN2 (0.74) | KMT2AMEN1GAAATMSMN1; SMN2 | |
| SCHEMBL28644956 | 0.77 | KMT2A (1.00) | KMT2AMEN1GAASMN1; SMN2POLB | |
| SCHEMBL10031630 | 0.77 | KMT2A (0.72) | KMT2AMEN1GAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102427853-A | Protease Inhibitors | ORION CORP | 2012-04-25 | — | — | CN | disclosed |
| EP-1395606-A1 | PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA | GLAXO GROUP LIMITED (GB) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002100886-A1 | PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA | GLAXO GROUP LIMITED (GB) | 2002-12-19 | — | — | WO | disclosed |