Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6560403

CC(C)(C1=CC=CC1)C1c2ccccc2-c2ccccc21.[Cl-].[Cl-].[Zr+2]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5175651 0.97 GPR3 (0.33) GPR3CYP1A2CYP2D6
SCHEMBL27669454 0.95 GPR3 (0.32) GPR3CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL7940232 0.89
Hydrochloric Acid SCHEMBL7603013 0.85 MEN1 (0.31)
Hydrochloric Acid SCHEMBL7931293 0.85
Hydrochloric Acid SCHEMBL7940430 0.85 MEN1 (0.31)
Hydrochloric Acid SCHEMBL8666939 0.82
Hydrochloric Acid SCHEMBL7939282 0.82
Hydrochloric Acid SCHEMBL7938762 0.82 MEN1 (0.33)
SCHEMBL8970974 0.81 GPR3 (0.32) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6683016-B1 SLURRYING METALLOCENE AND ACTIVATOR, APPLYING SONIC WAVES OR VIBRATION WAVES, WASHING WITH HYDROCARBON SOLVENT, DRYING; EVEN PENETRATION INTO PORE SPACE OF SUPPORT DAELIM INDUSTRIAL CO., LTD. (KR) 2004-01-27 US disclosed
EP-1042375-B1 SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH DAELIM IND CO LTD (KR) 2004-01-02 EP disclosed
US-6509427-B1 Cocatalyst and Group 4B, 5, or 6 metal complex comprising unsaturated compound with cyclopentadienyl, indenyl, or fluorenyl substituent; addition polymerization of olefins PHILLIPS PETROLEUM COMPANY 2003-01-21 US disclosed
EP-1042375-A1 SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH DAELIM INDUSTRIAL CO., LTD. (KR) 2000-10-11 EP disclosed
WO-2000023483-A1 SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH DAELIM INDUSTRIAL CO., LTD. (KR) 2000-04-27 WO disclosed
US-5583189-A USING A CATALYST SYSTEM COMPRISING THE REACTION PRODUCT OF A METALLOCENE COMPOUND, A SOLID ORGANOALUMINOXY PRODUCT AND AN ORGANOMETAL COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1996-12-10 US disclosed
US-5496781-A OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1996-03-05 US disclosed
US-5480948-A WITH CATALYST OF /A/ORGANOALUMINOXY PRODUCT FORMED BY REACTING ORGANOALUMINOXANE AND ORGANIC PEROXIDE, ALKYLENE OXIDE OR ORGANIC CARBONATE AND /B/GROUP IVB OR VB METAL HYDROCARBYL, CYCLOPENTADIENYL, ALKOXIDE, ARYLOXIDE, HALIDE OR HYDRIDE PHILLIPS PETROLEUM COMPANY (US) 1996-01-02 US disclosed
EP-0683179-A1 Metallocene catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-11-22 EP disclosed
EP-0677526-A1 Organoaluminoxy product, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-10-18 EP disclosed
US-5436212-A Coordination polymerization catalysts for olefins PHILLIPS PETROLEUM COMPANY (US) 1995-07-25 US disclosed
US-5420320-A Method for preparing cyclopentadienyl-type ligands and metallocene compounds PHILLIPS PETROLEUM COMPANY (US) 1995-05-30 US disclosed