SCHEMBL6560418

SCHEMBL6560418

CCCCCCCCCCCCCCCCCCCCCCOC(=O)C(CCCCCCCCCCCCCCCC)CC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.53
MMP2 P08253 6/20 0.48
MMP9 P14780 1/20 0.48
MMP12 P39900 1/20 0.48
MMP3 P08254 5/20 0.48
MMP1 P03956 3/20 0.48
MMP7 P09237 1/20 0.48
NAAA Q02083 1/20 0.47
MAPT P10636 1/20 0.46
HCAR2 Q8TDS4 1/20 0.45
EPHX1 P07099 1/20 0.44
CA2 P00918 1/20 0.44
GRIK1 P39086 1/20 0.44
GRIK2 Q13002 1/20 0.44
FFAR4 Q5NUL3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27489587 1.00 GPR84 (0.53) GPR84MMP2MMP9MMP12MMP3
SCHEMBL14672526 1.00 GPR84 (0.53) GPR84MMP2MMP9MMP12MMP3
SCHEMBL27774117 1.00 GPR84 (0.53) GPR84MMP2MMP9MMP12MMP3
SCHEMBL14672449 1.00 GPR84 (0.53) GPR84MMP2MMP9MMP12MMP3
SCHEMBL27940710 1.00 GPR84 (0.53) GPR84MMP2MMP9MMP12MMP3
SCHEMBL5180252 1.00 GPR84 (0.53) GPR84MMP2MMP9MMP12MMP3
SCHEMBL11655019 1.00 GPR84 (0.53) GPR84MMP2MMP9MMP12MMP3
Ammonia Solution, Strong SCHEMBL11795927 0.98 GPR84 (0.51) GPR84MMP2MMP9MMP12MMP3
SCHEMBL27900722 0.98 GPR84 (0.51) GPR84MMP2MMP9MMP12MMP3
SCHEMBL8749767 0.97 GPR84 (0.53) GPR84MMP2MMP9MMP12MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0793481-B1 COSMETIC COMPOSITION CONTAINING HYDROXY ALKANOATE DERIVATIVES UNILEVER PLC (GB) 2004-06-02 EP disclosed
EP-0695167-B1 COSMETIC COMPOSITION CONTAINING CERAMIDE PRECURSORS UNILEVER PLC (GB) 1997-12-17 EP disclosed
EP-0793481-A1 COSMETIC COMPOSITION CONTAINING HYDROXY ALKANOATE DERIVATIVES UNILEVER PLC (GB) 1997-09-10 EP disclosed
US-5650158-A Skin-conditioning succinic acid derivatives HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1997-07-22 US disclosed
US-5578641-A TETRAACETYL PHYTOSPHINGOSINE AS CERAMIDE PATHWAY INTERMEDIATE IN COSMETICALLY ACCEPTABLE VEHICLE, FOR TOPICAL APPLICATION TO HUMAN SKIN ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) 1996-11-26 US disclosed
EP-0695167-A1 COSMETIC COMPOSITION CONTAINING CERAMIDE PRECURSORS UNILEVER PLC (GB) 1996-02-07 EP disclosed
WO-1995005159-A1 ACYLATED HYDROXYALKANOATES AND THEIR USES UNILEVER PLC (GB) 1995-02-23 WO disclosed
WO-1995005153-A1 COSMETIC COMPOSITION CONTAINING HYDROXY ALKANOATE DERIVATIVES UNILEVER PLC (GB) 1995-02-23 WO disclosed
WO-1994023694-A1 COSMETIC COMPOSITION CONTAINING CERAMIDE PRECURSORS UNILEVER PLC (GB) 1994-10-27 WO disclosed