Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.53 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 5/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27468991 | 1.00 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL27452367 | 1.00 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL14672526 | 0.97 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL6560418 | 0.97 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL27774117 | 0.97 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL14672449 | 0.97 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL5180252 | 0.97 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL11655019 | 0.97 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL27940710 | 0.97 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 | |
| SCHEMBL27489587 | 0.97 | GPR84 (0.53) | GPR84MMP2MMP9MMP12MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763012-A1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032944-A1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-07 | — | — | WO | disclosed |