Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679737 | 0.86 | HTT (0.53) | UTS2RRAB9AMLYCDLMNA | |
| SCHEMBL4682046 | 0.84 | SMN1; SMN2 (0.64) | NPC1RAB9AMLYCDLMNA | |
| SCHEMBL6559629 | 0.84 | CA12 (0.53) | CES2CES1MLYCDLMNA | |
| SCHEMBL6559620 | 0.80 | CES2 (0.56) | CES2CES1GSK3BTRPV1PTGS1 | |
| SCHEMBL12251427 | 0.78 | MLYCD (0.71) | CES2CES1GSK3BTRPV1PTGS1 | |
| SCHEMBL5856471 | 0.76 | CES2 (0.53) | CES2CES1GSK3BTRPV1PTGS1 | |
| SCHEMBL27244131 | 0.76 | MEN1 (0.54) | CES2CES1GSK3BPTGS1NPC1 | |
| SCHEMBL6559614 | 0.75 | GRN (0.49) | RAB9A | |
| SCHEMBL20963126 | 0.75 | MLYCD (0.53) | CES2CES1GSK3BTRPV1PTGS1 | |
| SCHEMBL13753437 | 0.75 | MLYCD (0.53) | CES2CES1GSK3BTRPV1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035113-B1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds | BASF AG (DE) | 2004-10-06 | — | — | EP | claimed |
| US-6596902-B2 | Useful for insecticides and the control of acarid pests; chemical intermediates in the preparation of arylpyrrole compounds such as chlorfenapyr | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | claimed |
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AMERICAN CYANAMID COMPANY | 2002-04-25 | — | — | US | claimed |
| CN-1267667-A | Process for producing 2-aryl-5-(perfluoroalkyl) pyrrole compound from N-[1-chlorine-1-(perfluoroalkyl) quadri group] imido aryl chlorine compound | AMERICAN CYANAMID CO (US) | 2000-09-27 | — | — | CN | claimed |
| EP-1035113-A2 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds | American Cyanamid Company (US) | 2000-09-13 | — | — | EP | claimed |
| EP-1035113-B1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds | BASF AG (DE) | 2004-10-06 | — | — | EP | disclosed |
| US-6596902-B2 | Useful for insecticides and the control of acarid pests; chemical intermediates in the preparation of arylpyrrole compounds such as chlorfenapyr | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AMERICAN CYANAMID COMPANY | 2002-04-25 | — | — | US | disclosed |
| US-6320059-B1 | REACTING N-(1-CHLORO-1-(PERFLUOROALKYL)METHYL)ARYLIMIDOYL CHLORIDE COMPOUND WITH DIENEOPHILE COMPOUND OR SUBSTITUTED HALOETHANE COMPOUND, AND BASE, IN PRESENCE OF SOLVENT | AMERICAN CYANAMID COMPANY | 2001-11-20 | — | — | US | disclosed |
| CN-1267667-A | Process for producing 2-aryl-5-(perfluoroalkyl) pyrrole compound from N-[1-chlorine-1-(perfluoroalkyl) quadri group] imido aryl chlorine compound | AMERICAN CYANAMID CO (US) | 2000-09-27 | — | — | CN | disclosed |
| EP-1035113-A2 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl)methyl]arylimidoyl chloride compounds | American Cyanamid Company (US) | 2000-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AFF1, AFF4, AFF2 | CES2 1796/4885CES1 729/4885GSK3B 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.