SCHEMBL6560492

SCHEMBL6560492

O=CC(=O)CCC1CC1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 10/20 0.47
HTR2B P41595 6/20 0.47
HTR2A P28223 4/20 0.47
MAOB P27338 2/20 0.47
CNR1 P21554 1/20 0.41
HDAC4 P56524 1/20 0.39
KDM1A O60341 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 1/20 0.38
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
DAO P14920 1/20 0.38
SCN3A Q9NY46 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6560502 0.83 HTR2C (0.53) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL6560516 0.83 HTR2C (0.53) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL6228607 0.77 HTR2C (0.50) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL6228608 0.77 HTR2C (0.50) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL6560505 0.76 HTR2C (0.53) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL6130290 0.75 HTR2C (0.57) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL6130292 0.75 HTR2C (0.57) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL9383123 0.73 HTR2C (0.50) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL9383126 0.73 HTR2C (0.50) HTR2CHTR2BHTR2AMAOBCNR1
SCHEMBL25262357 0.73 HTR2C (0.59) HTR2CHTR2BHTR2AMAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1120403-B1 Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides DOW AGROSCIENCES LLC (US) 2004-03-17 EP disclosed
US-6313339-B1 Aryl and heteroarylcylopropyl oxime ethers and their use as fungicides and insecticides ROHM AND HAAS ASIA, INC. 2001-11-06 US disclosed
EP-1120403-A2 Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides ROHM AND HAAS COMPANY (US) 2001-08-01 EP disclosed