Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.53 |
| ▸ | HTR2B | P41595 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383123 | 0.89 | HTR2C (0.50) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL9383126 | 0.89 | HTR2C (0.50) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL25254330 | 0.81 | HTR2C (0.57) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL13778 | 0.81 | HTR2C (0.57) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL13777 | 0.81 | HTR2C (0.57) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL6560492 | 0.76 | HTR2C (0.47) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL5680153 | 0.75 | HTR2C (0.70) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL25262357 | 0.75 | HTR2C (0.59) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL6560502 | 0.74 | HTR2C (0.53) | HTR2CMAOBHTR2BHTR2ADRD2 | |
| SCHEMBL6560516 | 0.74 | HTR2C (0.53) | HTR2CMAOBHTR2BHTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120403-B1 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6313339-B1 | Aryl and heteroarylcylopropyl oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS ASIA, INC. | 2001-11-06 | — | — | US | disclosed |
| EP-1120403-A2 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |