Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | RARG | P13631 | 3/20 | 0.35 |
| ▸ | HNF4A | P41235 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479338 | 0.86 | RXRA (0.47) | RXRAPPARGNR1H3RARARARB | |
| SCHEMBL6874366 | 0.85 | RXRA (0.49) | RXRAPPARGNR1H3RARARARB | |
| SCHEMBL6033311 | 0.84 | RARA (0.46) | RXRAPPARGNR1H3RARARARB | |
| SCHEMBL5364822 | 0.83 | RXRA (0.48) | RXRAPPARGNR1H3RARARARB | |
| SCHEMBL6033082 | 0.82 | RXRA (0.43) | RXRAPPARGNR1H3RARARARB | |
| SCHEMBL8037984 | 0.79 | RXRA (0.36) | RXRAPPARGNR1H3RARARARB | |
| SCHEMBL8005483 | 0.79 | RXRA (0.50) | RXRARARARARBRARGHNF4A | |
| SCHEMBL8522363 | 0.77 | RXRA (0.37) | RXRAPPARGNR1H3RARARARB | |
| SCHEMBL5846268 | 0.76 | RXRA (0.36) | RXRARARARARBRARGHNF4A | |
| SCHEMBL8522361 | 0.75 | RXRA (0.34) | RXRAPPARGNR1H3RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086080-B1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2004-08-25 | — | — | EP | disclosed |
| EP-0826657-B1 | Compounds for modulation of hormone receptors, compositions containing them and their use in therapy | CT INTERNAT DE RECH S (FR) | 2001-08-01 | — | — | EP | disclosed |
| EP-1086080-A1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065872-A1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 1999-12-23 | — | — | WO | disclosed |
| EP-0826657-A1 | Compounds for modulation of hormone receptors, compositions containing them and their use in therapy | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1998-03-04 | — | — | EP | disclosed |