Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.65 |
| ▸ | ADK | P55263 | 3/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.55 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.55 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197163 | 1.00 | TYMP (0.68) | TYMPADORA3ADKADORA1P2RY1 | |
| SCHEMBL7197169 | 1.00 | TYMP (0.68) | TYMPADORA3ADKADORA1P2RY1 | |
| SCHEMBL21480367 | 0.90 | TYMP (0.56) | TYMPADORA3ADKADORA1P2RY1 | |
| SCHEMBL8207328 | 0.88 | TYMP (0.68) | TYMPADORA3ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL41365 | 0.87 | ADORA3 (0.66) | ADORA3ADKADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL780585 | 0.87 | ADORA3 (0.66) | ADORA3ADKADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL20414121 | 0.87 | TYMP (0.62) | TYMPADORA3ADORA1SMN1; SMN2ADORA2A | |
| SCHEMBL15926827 | 0.86 | ADORA1 (0.74) | ADORA3ADORA1P2RY1SMN1; SMN2SRC | |
| SCHEMBL384075 | 0.86 | ADORA1 (0.74) | ADORA3ADORA1P2RY1SMN1; SMN2SRC | |
| SCHEMBL15788449 | 0.86 | ADORA1 (0.74) | ADORA3ADORA1P2RY1SMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030856-B1 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-6740644-B2 | ADENOSINE DERIVATIVES, AGONISTS AT THE ADENOSINE A1 RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2004-05-25 | — | — | US | disclosed |
| EP-1397147-A1 | USE OF ADENOSINE A1 AGONISTS IN THE TREATMENT OF EMESIS | GLAXO GROUP LIMITED (GB) | 2004-03-17 | — | — | EP | disclosed |
| US-20030158146-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2003-08-21 | — | — | US | disclosed |
| WO-2002069982-A1 | MEDICAMENTS | GLAXO GROUP LIMITED (GB) | 2002-09-12 | — | — | WO | disclosed |
| EP-1030856-A2 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024451-A2 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 1999-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158146-A1 | Chemical compounds | CNR1, ADORA3, ADORA1 | TYMP 4423/4885ADORA3 2/4885ADK 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.