Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.68 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197169 | 0.88 | TYMP (0.68) | TYMPP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL6560740 | 0.88 | TYMP (0.68) | TYMPP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL7197163 | 0.88 | TYMP (0.68) | TYMPP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL17440176 | 0.87 | ADORA1 (0.76) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL481524 | 0.87 | ADORA1 (0.76) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL2040670 | 0.87 | ADORA1 (0.76) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL91050 | 0.85 | SLC29A1 (0.73) | TYMPADORA1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL3164068 | 0.85 | SLC29A1 (0.73) | TYMPADORA1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL272122 | 0.85 | SLC29A1 (0.73) | TYMPADORA1SMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL21139429 | 0.85 | SLC29A1 (0.73) | TYMPADORA1SMN1; SMN2ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043228-A | O6 -substituted guanine derivatives, a process for their preparation and their use in treating tumor cells | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-03-28 | — | — | US | claimed |