Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13345401 | 0.85 | MGAM (0.39) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL19107058 | 0.83 | ALOX15 (0.36) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL581924 | 0.82 | ALOX15 (0.50) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL5310540 | 0.82 | ALOX15 (0.50) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL18219006 | 0.82 | ALOX15 (0.41) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL18908300 | 0.82 | ALOX15 (0.41) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL18219051 | 0.82 | ALOX15 (0.41) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL29000852 | 0.82 | ALOX15 (0.50) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL18206327 | 0.80 | CYP2D6 (0.38) | ALOX15TSHRSMN1; SMN2LMNATDP1 | |
| SCHEMBL13377668 | 0.80 | MMP1 (0.39) | ALOX15TSHRSMN1; SMN2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398312-A1 | Beta-substituted-gamma-butyrolactones and a process for preparation thereof | Uh, Hong-Sun (KR) | 2004-03-17 | — | — | EP | disclosed |