Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197709 | 0.65 | TYMP (0.38) | TYMPPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL6086721 | 0.64 | TYMP (0.37) | TYMPPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL6086452 | 0.64 | PDE3B (0.38) | TYMPPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL1484445 | 0.64 | POLB (0.40) | TYMPPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL12752299 | 0.63 | ALDH1A1 (0.32) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6085497 | 0.63 | PDE3B (0.41) | TYMPPDE3BPDE3AKDM4EMAPT | |
| SCHEMBL14423060 | 0.61 | TYMP (0.47) | TYMPPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL9016405 | 0.60 | TYMP (0.39) | TYMPPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL17584937 | 0.58 | KDM4E (0.50) | PDE3BPDE3AKDM4EALDH1A1GAA | |
| SCHEMBL28164986 | 0.57 | ALDH1A1 (0.35) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035116-B1 | Process for the preparation of 1-[(cyclopent-3-en-1-yl)-methyl]-5-ethyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione | SAMJIN PHARM CO LTD (KR) | 2004-02-11 | — | — | EP | disclosed |
| US-6274732-B1 | ALKYLATION | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2001-08-14 | — | — | US | disclosed |
| EP-1035116-A1 | Process for the preparation of 1-[(cyclopent-3-en-1-yl)-methyl]-5-ethyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione | Samjin Pharmaceutical Co., Ltd. (KR) | 2000-09-13 | — | — | EP | disclosed |