Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28308497 | 0.73 | GRIN2D (0.30) | — | |
| SCHEMBL23595534 | 0.72 | GRIN1 (0.39) | TSHR | |
| SCHEMBL23595725 | 0.70 | LMNA (0.46) | TSHR | |
| SCHEMBL23595643 | 0.69 | GRIN1 (0.36) | TSHR | |
| SCHEMBL23595726 | 0.68 | LMNA (0.38) | TSHRPOLB | |
| SCHEMBL11818817 | 0.67 | HTT (0.35) | HTTPOLBALDH1A1 | |
| SCHEMBL15502281 | 0.65 | ALDH1A1 (0.35) | HTTPOLBALDH1A1 | |
| SCHEMBL4811675 | 0.64 | MAPT (0.41) | MAPTCYP2C9TSHRALDH1A1CYP3A4 | |
| SCHEMBL1254598 | 0.64 | MAPT (0.31) | MAPTCYP2C9TSHRCYP3A4CYP2C19 | |
| SCHEMBL1749522 | 0.64 | CYP3A4 (0.32) | MAPTCYP2C9TSHRCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933993-A4 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0933993-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS INC. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997047194-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |