Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 8/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308208 | 0.90 | ALDH1A1 (0.55) | KMT2AMEN1POLBALDH1A1L3MBTL1 | |
| SCHEMBL8121589 | 0.86 | ALDH1A1 (0.47) | KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL8285876 | 0.83 | ALDH1A1 (0.54) | KCNA5TACR3KMT2AMEN1POLB | |
| SCHEMBL27929589 | 0.83 | KMT2A (0.43) | KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL9298256 | 0.82 | EEF2K (0.48) | POLBALDH1A1L3MBTL1 | |
| SCHEMBL5691034 | 0.82 | EEF2K (0.48) | POLBALDH1A1L3MBTL1 | |
| SCHEMBL2347309 | 0.82 | HPGD (0.57) | KCNA5KMT2APOLBALDH1A1HPGD | |
| SCHEMBL14514066 | 0.81 | TACR3 (0.50) | KCNA5TACR3KMT2AMEN1POLB | |
| SCHEMBL15170380 | 0.81 | KMT2A (0.53) | KCNA5TACR3KMT2AMEN1POLB | |
| SCHEMBL15170378 | 0.81 | KMT2A (0.53) | KCNA5TACR3KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319664-B1 | Process for the preparation of organozinc halogen compounds from reactive halogen compounds and use thereof | CONSORTIUM ELEKTROCHEM IND (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6605716-B2 | By Reformatsky rearrangement of aldehydes, ketones, or imines in presence of zinc | CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIES, GMBH (DE) | 2003-08-12 | — | — | US | disclosed |
| US-6603034-B2 | Reacting a reactive halogen compound with zinc in one or more carboxylic esters. It is also possible to prepare keto, hydroxyl and amino compounds of organozinc halides obtained in a first step from a reactive halogen compound and zinc in one | Consortium für elektrochemische Industrie GmbH (DE) | 2003-08-05 | — | — | US | disclosed |
| US-20030114697-A1 | PREPARATION OF ORGANOZINC HALIDES FROM REACTIVE HALOGEN COMPOUNDS AND THEIR USE | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2003-06-19 | — | — | US | disclosed |
| EP-1319664-A1 | Process for the preparation of organozinc halogen compounds from reactive halogen compounds and use thereof | Consortium für elektrochemische Industrie GmbH (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-20020013501-A1 | Process for the preparation of hydroxy and amino compounds | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-01-31 | — | — | US | disclosed |
| EP-1167325-A1 | Process for preparing hydroxy and amino compounds | Consortium für elektrochemische Industrie GmbH (DE) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013501-A1 | Process for the preparation of hydroxy and amino compounds | BCKDK, KHK, HRH1 | KCNA5 4165/4885TACR3 3088/4885KMT2A 645/4885 |
| US-20030114697-A1 | PREPARATION OF ORGANOZINC HALIDES FROM REACTIVE HALOGEN COMPOUNDS AND THEIR USE | ZRANB2, ZKSCAN2, ZCCHC8 | KCNA5 743/4885TACR3 1622/4885KMT2A 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.