Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 19/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561257 | 0.88 | ITGA4 (0.64) | ITGA4ITGB1 | |
| SCHEMBL6562462 | 0.88 | ITGA4 (0.64) | ITGA4ITGB1 | |
| SCHEMBL6561253 | 0.88 | ITGA4 (0.64) | ITGA4ITGB1 | |
| SCHEMBL7105344 | 0.84 | ITGA4 (0.47) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL6560210 | 0.81 | ITGA4 (0.63) | ITGA4ITGB1 | |
| SCHEMBL6560206 | 0.81 | ITGA4 (0.63) | ITGA4ITGB1 | |
| SCHEMBL6561631 | 0.81 | ITGA4 (0.63) | ITGA4ITGB1 | |
| SCHEMBL7098651 | 0.78 | MEN1 (0.42) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL7103946 | 0.74 | ITGA4 (0.39) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL6563489 | 0.74 | ITGA4 (0.53) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |