SCHEMBL6561322

SCHEMBL6561322

CC(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(N)C1CCCC21

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 20/20 0.69
NOS3 P29474 18/20 0.69
NOS2 P35228 18/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6069274 0.99 NOS1 (0.71) NOS1NOS3NOS2
SCHEMBL6560391 0.89 NOS1 (0.66) NOS1NOS3NOS2
Hydrochloric Acid SCHEMBL6069891 0.88 NOS1 (0.67) NOS1NOS3NOS2
SCHEMBL6561362 0.87 NOS1 (0.63) NOS1NOS3NOS2
Hydrochloric Acid SCHEMBL6069438 0.86 NOS1 (0.64) NOS1NOS3NOS2
SCHEMBL6561433 0.83 NOS1 (0.98) NOS1NOS3NOS2
Hydrochloric Acid SCHEMBL6069807 0.82 NOS1 (1.00) NOS1NOS3NOS2
SCHEMBL6561325 0.78 NOS1 (0.98) NOS1NOS3NOS2
Hydrochloric Acid SCHEMBL6069276 0.78 NOS1 (1.00) NOS1NOS3NOS2
SCHEMBL6069590 0.77 NOS3 (0.42) NOS1NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115708-B1 AMINOALKYL-3,4-DIHYDROQUINOLINE DERIVATES AS NO-SYNTHASE INHIBITORS SCHERING AG (DE) 2004-04-14 EP claimed