Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560817 | 0.80 | HSD17B10 (0.57) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL7805578 | 0.79 | HTR7 (0.48) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7805593 | 0.75 | HTR7 (0.52) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6559765 | 0.74 | HTR7 (0.53) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7803866 | 0.74 | HTR7 (0.53) | HTR7ALDH1A1KDM4ESMN1; SMN2FABP3 | |
| SCHEMBL11381008 | 0.73 | DCTPP1 (0.51) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL5781445 | 0.72 | HTR7 (0.48) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL7949388 | 0.71 | HTR7 (0.60) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| Hydrochloric Acid SCHEMBL5785010 | 0.71 | HTR7 (0.47) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL6563153 | 0.71 | HTR7 (0.56) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |