Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.59 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560810 | 0.79 | ADORA2A (0.76) | NR1H2NR1H3HPGDSADORA2ANPC1 | |
| SCHEMBL10713687 | 0.76 | NR1H2 (0.56) | NR1H2NR1H3HPGDSADORA2ANPC1 | |
| SCHEMBL646494 | 0.76 | NR1H2 (0.76) | NR1H2NR1H3HPGDSADORA2ANPC1 | |
| SCHEMBL28148107 | 0.76 | NR1H2 (0.65) | NR1H2NR1H3HPGDSADORA2ANPC1 | |
| SCHEMBL6561489 | 0.76 | HTR7 (0.62) | NR1H2NR1H3HPGDSSMN1; SMN2ALDH1A1 | |
| SCHEMBL666693 | 0.75 | NR1H2 (1.00) | NR1H2NR1H3HPGDSADORA2ANPC1 | |
| SCHEMBL17280024 | 0.74 | NR1H2 (0.61) | NR1H2NR1H3HPGDSADORA2ANPC1 | |
| SCHEMBL17574086 | 0.74 | NR1H2 (0.96) | NR1H2NR1H3HPGDSADORA2ANPC1 | |
| SCHEMBL1071190 | 0.74 | NR1H2 (0.96) | NR1H2NR1H3HPGDSADORA2ANPC1 | |
| SCHEMBL26109969 | 0.74 | NR1H2 (0.96) | NR1H2NR1H3HPGDSADORA2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-B1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-07-07 | — | — | EP | disclosed |
| US-6255327-B1 | ANTIHYPOXC, ANTIISCHEMIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-07-03 | — | — | US | disclosed |
| EP-1071670-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054314-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |