Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891719 | 0.81 | EPHX2 (0.72) | EPHX2NR1H4TRPV1 | |
| SCHEMBL6563007 | 0.80 | EPHX2 (0.63) | EPHX2NR1H4TRPV1 | |
| SCHEMBL4625376 | 0.80 | EPHX2 (0.57) | EPHX2NR1H4TRPV1CA1CA2 | |
| SCHEMBL22059471 | 0.75 | EPHX2 (1.00) | EPHX2NR1H4CA1CA2 | |
| SCHEMBL4624020 | 0.72 | EPHX2 (0.59) | EPHX2NR1H4TRPV1 | |
| Hydrochloric Acid SCHEMBL5803678 | 0.71 | EPHX2 (0.61) | EPHX2NR1H4CA1CA2 | |
| SCHEMBL4891046 | 0.70 | CA1 (0.73) | EPHX2NR1H4TRPV1CA1CA2 | |
| SCHEMBL4890410 | 0.69 | CA1 (0.69) | EPHX2NR1H4TRPV1CA1CA2 | |
| SCHEMBL1107981 | 0.68 | ALDH1A1 (0.64) | EPHX2NR1H4CA1CA2 | |
| SCHEMBL4623706 | 0.68 | TRPV1 (0.66) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303483-A4 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORP (KR) | 2004-11-03 | — | — | EP | disclosed |
| EP-1303483-A1 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002016318-A1 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2002-02-28 | — | — | WO | disclosed |