SCHEMBL6561395

SCHEMBL6561395

C=C(C)C(=O)OCCOc1ccc(C[C](C)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.58
APEX1 P27695 1/20 0.58
HTT P42858 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
THRB P10828 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
PDE4A P27815 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
ALDH1A1 P00352 2/20 0.42
PLA2G4B P0C869 1/20 0.41
FFAR1 O14842 1/20 0.40
LTB4R Q15722 2/20 0.40
LTB4R2 Q9NPC1 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL454606 0.87 POLB (0.67) POLBAPEX1HTTTDP1LMNA
SCHEMBL17036777 0.86 POLB (0.58) POLBAPEX1HTTTDP1LMNA
SCHEMBL331665 0.86 POLB (0.58) POLBAPEX1HTTTDP1LMNA
SCHEMBL25402465 0.85 POLB (0.61) POLBAPEX1HTTTDP1LMNA
SCHEMBL2154214 0.84 ALDH1A1 (0.58) POLBAPEX1HTTTDP1LMNA
SCHEMBL6561399 0.83 POLB (0.52) POLBAPEX1HTTTDP1LMNA
SCHEMBL14173271 0.83 POLB (0.61) POLBAPEX1HTTTDP1LMNA
SCHEMBL4447276 0.83 POLB (0.61) POLBAPEX1HTTTDP1L3MBTL1
SCHEMBL11053172 0.83 POLB (0.61) POLBAPEX1HTTTDP1LMNA
SCHEMBL21371 0.83 TDP1 (0.61) POLBAPEX1HTTTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882749-B1 Urethane prepolymer, process for producing the same and pressure-sensitive adhesive comprising the same KYOEISHA CHEMICAL CO LTD (JP) 2004-03-24 EP claimed
CN-104812853-A Composition for hardcoat and molded article with hardcoat layer KYOEISHA CHEMICAL CO LTD 2015-07-29 CN disclosed