Hydroxytyrosol

Hydroxytyrosol

SCHEMBL6561419

OCCc1ccc(O)c(O)c1.OCCc1ccc(O)cc1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.83
MAPT P10636 4/20 0.83
ALDH1A1 P00352 2/20 0.83
GAA P10253 2/20 0.83
ALOX5 P09917 1/20 0.83
BACE1 P56817 1/20 0.83
ALOX15 P16050 6/20 0.74
IGF1R P08069 5/20 0.74
CA2 P00918 3/20 0.71
MAPK1 P28482 4/20 0.55
ADRA2A P08913 3/20 0.55
DRD2 P14416 3/20 0.55
DRD1 P21728 3/20 0.55
DRD4 P21917 3/20 0.55
SLC6A2 P23975 3/20 0.55
DRD3 P35462 3/20 0.55
SLC6A3 Q01959 3/20 0.55
DRD5 P21918 2/20 0.55
RECQL P46063 2/20 0.55
TDP1 Q9NUW8 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxytyrosol SCHEMBL44363 0.91 MAPT (1.00) KDM4EMAPTALDH1A1GAAALOX5
Hydroxytyrosol SCHEMBL29414541 0.91 MAPT (1.00) KDM4EMAPTALDH1A1GAAALOX5
SCHEMBL28999489 0.89 ALOX15 (0.83) KDM4EMAPTALDH1A1GAAALOX5
Tyrosol SCHEMBL43838 0.84 CA2 (1.00) KDM4EMAPTALDH1A1GAAALOX5
Tyrosol SCHEMBL28609607 0.82 CA2 (0.94) KDM4EMAPTALDH1A1GAAALOX5
SCHEMBL8431254 0.82 ALOX15 (0.76) KDM4EMAPTALDH1A1GAAALOX5
Dopamine SCHEMBL2723670 0.82 KDM4E (0.84) KDM4EMAPTALDH1A1GAAALOX5
SCHEMBL11811815 0.80 ALOX15 (0.69) KDM4EMAPTALDH1A1GAAALOX5
SCHEMBL107956 0.79 ALOX15 (0.80) KDM4EMAPTALDH1A1GAAALOX5
SCHEMBL30631592 0.79 ALOX15 (0.80) KDM4EMAPTALDH1A1GAAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899221-A Composition for skin based on algae and olive leaf extract 医疗品牌研究有限公司 2016-08-24 CN disclosed
EP-1239734-A4 ANTIOXIDANT COMPOSITIONS EXTRACTED FROM OLIVES AND OLIVE BY-PRODUCTS USANA INC (US) 2004-07-14 EP disclosed
EP-1239734-A1 ANTIOXIDANT COMPOSITIONS EXTRACTED FROM OLIVES AND OLIVE BY-PRODUCTS Usana, Inc. (US) 2002-09-18 EP disclosed
WO-2001045514-A1 ANTIOXIDANT COMPOSITIONS EXTRACTED FROM OLIVES AND OLIVE BY-PRODUCTS USANA, INC. (US) 2001-06-28 WO disclosed