Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 12/20 | 0.57 |
| ▸ | PPARG | P37231 | 10/20 | 0.57 |
| ▸ | PPARA | Q07869 | 9/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561529 | 0.83 | PPARD (0.62) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6560732 | 0.81 | PPARD (0.53) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6559190 | 0.75 | PPARD (0.52) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6559843 | 0.75 | PPARD (0.60) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6561712 | 0.73 | PPARD (0.55) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6561590 | 0.73 | PPARD (0.82) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6558756 | 0.73 | PPARD (0.79) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6561585 | 0.72 | PPARD (1.00) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6934158 | 0.72 | PPARD (0.66) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6931405 | 0.72 | PPARD (0.69) | PPARDPPARGPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |