Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560271 | 1.00 | HTT (0.47) | HTTMAPTLMNAKDM4EF2 | |
| SCHEMBL5238501 | 0.79 | HTT (0.71) | HTTMAPTLMNAKDM4EKMT2A | |
| SCHEMBL29277477 | 0.78 | ELANE (0.56) | MAPTLMNAF2KMT2AMEN1 | |
| SCHEMBL10029748 | 0.76 | F2 (0.42) | MAPTLMNAKDM4EF2KMT2A | |
| SCHEMBL5582384 | 0.75 | CHRNA7 (0.49) | MAPTLMNAF2KMT2AMEN1 | |
| SCHEMBL27598256 | 0.75 | CHRNA7 (0.49) | MAPTLMNAF2KMT2AMEN1 | |
| SCHEMBL2696973 | 0.75 | CHRNA7 (0.49) | MAPTLMNAF2KMT2AMEN1 | |
| SCHEMBL5401016 | 0.74 | ELANE (0.55) | HTTLMNAF2KMT2AMEN1 | |
| SCHEMBL5788955 | 0.72 | ELANE (0.58) | HTTLMNAF2KMT2AMEN1 | |
| SCHEMBL28937493 | 0.72 | SLC6A3 (0.50) | MAPTLMNAF2KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398312-A1 | Beta-substituted-gamma-butyrolactones and a process for preparation thereof | Uh, Hong-Sun (KR) | 2004-03-17 | — | — | EP | claimed |