Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561971 | 0.91 | ALDH1A1 (0.48) | RAB9AALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL7677322 | 0.85 | ALDH1A1 (0.44) | RAB9AALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL6563427 | 0.78 | ACACB (0.49) | ALDH1A1HPGDSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL3215328 | 0.77 | ALDH1A1 (0.61) | RAB9AALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL6563532 | 0.76 | ALDH1A1 (0.44) | RAB9AALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL13445156 | 0.72 | MAPT (0.60) | RAB9AALDH1A1HTTL3MBTL1MMP2 | |
| SCHEMBL13063666 | 0.72 | MAPT (0.60) | RAB9AALDH1A1HTTL3MBTL1MMP2 | |
| SCHEMBL1615179 | 0.72 | ALDH1A1 (0.65) | RAB9AALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL9967905 | 0.72 | MAPT (0.60) | RAB9AALDH1A1HTTL3MBTL1MMP2 | |
| SCHEMBL13063665 | 0.72 | MAPT (0.60) | RAB9AALDH1A1HTTL3MBTL1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |