Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 6/20 | 0.40 |
| ▸ | F2 | P00734 | 6/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 5/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561971 | 0.88 | ALDH1A1 (0.48) | ALDH1A1RAB9ASMN1; SMN2HPGDHTT | |
| SCHEMBL6561903 | 0.85 | RAB9A (0.46) | ALDH1A1RAB9ASMN1; SMN2HPGDHTT | |
| SCHEMBL6563640 | 0.79 | ACACB (0.47) | ALDH1A1SMN1; SMN2HPGDL3MBTL1F10 | |
| SCHEMBL6563625 | 0.78 | PRSS1 (0.43) | ALDH1A1RAB9AHPGDL3MBTL1F7 | |
| SCHEMBL6564460 | 0.73 | ACACB (0.51) | HPGDF7F2F10PRSS1 | |
| SCHEMBL1615179 | 0.70 | ALDH1A1 (0.65) | ALDH1A1RAB9ASMN1; SMN2HPGDHTT | |
| SCHEMBL8305355 | 0.70 | ALOX5 (0.58) | — | |
| SCHEMBL7146207 | 0.70 | F2 (0.53) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL6563277 | 0.69 | F2 (0.41) | F7F2MAPK13MAPK12MAPK11 | |
| SCHEMBL18574217 | 0.68 | ASIC3 (0.71) | F7F2ASIC3F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |