Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 3/20 | 0.74 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.74 |
| ▸ | TNF | P01375 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431694 | 0.87 | TNF (0.70) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL9431028 | 0.87 | TNF (0.74) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL15014103 | 0.85 | TNF (0.72) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL12771519 | 0.85 | GALR3 (1.00) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL28227656 | 0.85 | MAPT (0.77) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL231295 | 0.84 | TNF (1.00) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL3100051 | 0.84 | TNF (0.70) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL3092835 | 0.84 | TNF (0.75) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL15567678 | 0.84 | TNF (0.70) | GALR3NR2F2TNFMAPTTP53 | |
| SCHEMBL13181091 | 0.83 | TNF (0.68) | GALR3NR2F2TNFMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |